Abstract: In summer, the rainfall in Fushun occurs frequently and lasts for a long time. If there is a mine earthquake, the slope is very easy to be unstable and destroyed. The limit equilibrium method combined with the seepage field is used to analyze the slope stability, so that we can analyze the impact of mine earthquakes in the rainy season on the Fushun West Open-pit Mine.The results show that with the same rainfall intensity and the longer duration, the pore water pressure contour is denser, and the more closed areas of the contour are, the lower the safety factor of the slope is. At the same duration, the greater the rainfall intensity, the faster the pore water pressure contour map changes; Rainfall is the same, the smaller the rainfall intensity, the greater the range of rainfall infiltration; After adding the horizontal mine earthquake load factor, as the mine earthquake intensity increases, the slope safety factor decreases. There is a rainfall critical value for slope rainfall. When the rainfall does not reach the critical value, the safety factor of the slope decreases slowly, and when it reaches the critical value, the safety factor decreases rapidly. Rainfall and mine earthquake have a great impact on the safety of the slope, so the slope should be reinforced in advance.