Abstract: The Huangshui River Basin, an important upstream tributary of the upper reaches of the Yellow River, serves as the political, economic, and cultural center of Qinghai Province, and is also a region with a high incidence of geological disasters. Within this basin, various types of disasters occur frequently, resulting in significant economic losses and casualties. These disasters also exhibit distinct regional characteristics. Based on the analysis of landform, geological rock group, geological structure, hydrometeorology and human engineering activities in the Huangshui River Basin, the comprehensive classification standard of geological disaster susceptibility was established, and the susceptibility of landslide disaster in the Huangshui River Basin was categorized into five levels: extremely high, high, medium, low and very low. Using a matlab-based platform for catastrophe theory, the inherent relationships among various assessment factors are fully considered, and the single-point disaster risk evaluation is extended to regional disaster susceptibility evaluation. Validation of the assessment results through ROC analysis demonstrates the high accuracy of this method, providing theoretical support for geological disaster prevention and control.