Abstract: The "3S" technology and soil chemical methods were used to study the change and ecological restored effect of sandy desertification land in Yulin City of Mu Us sandy land during the past 45 years. The results show that: the intensity of sandy desertification land in the study area was mainly mild and moderate, and the restored mode was mainly artificial restoration; the distributed area and the intensity of sandy desertification land from 1975 to 2019 showed the desertification developed rapidly and then deteriorated, the development of sandy desertification from 1975 to 2007 was closely related to human activities such as overgrazing, wasteland reclamation and mineral resources development, and the reversal from 2007 to 2019 was closely related to the implementation of ecological control policies and control projects; the soil nutrient content of the artificial restored area was better than the natural restored area, the different causes of sandy desertification land was very different under the same natural restored conditions; combined the artificial restored method and the natural restored method, artificial vegetation construction is proved to be a effective way to promote natural vegetation restoring and ecological restoration in the study area.