Abstract: Landslide formation, evolution and resurrection have been a hot topic in the field of landslide disaster prevention and mitigation. In the paper, based on analysis of the geological environment background and field survey, remote sensing interpretation, and experimental testing of large-scale landslides in the Jianzha Basin on the upper Yellow River, then taking the Simencun Landslide on the southern bank of the Yellow River in the basin as an example, the deformation process, characteristics of the landslide slip zone soil and accumulated body are discussed, the landslide formation process are reduction and reactive factors determined. Finally, some suggestions for the development and utilization of landslide deposits in the upper reaches of the Yellow River are put forward. It is believed that:(1) The landslide that was the old landslide occurred before 2005, which reactivated by the river-side erosion and artificial irrigation in spring 2018.(2) Comprehensive management of landslides should be combined with land remediation and appropriate irrigation methods should be selected, which is of great significance for landslide disaster prevention and mitigation and landslide body development and utilization in the upper reaches of the Yellow River on the northeastern part of the Tibetan Plateau.