Abstract: Anti-slip piles are an important measure for seismic reinforcement of slopes. Determining the pile design thrust and installation position is a key prerequisite for anti-slide pile design. Most existing studies calculate the design thrust based on the critical sliding surface prior to slope reinforcement. However, this surface may not be the most critical after pile installation, which can lead to insufficient pile resistance. In addition, improper pile placement may cause localized slope instability. To address these issues, this paper combines the pseudo-dynamic method with the residual thrust method, proposing a calculation approach for the design thrust and installation range of anti-slip piles considering multiple potential sliding surfaces. A corresponding MATLAB program was developed, and the reliability of the method was verified by comparing with results from Geo-studio software. Taking a simple homogeneous soil slope as an example, the calculation procedure for design thrust and installation range is introduced, and the results of five different methods are compared. The study emphasizes the importance of analyzing multiple potential sliding surfaces and highlights the superiority of the proposed method in preventing localized slope failure and inadequate design thrust after pile installation. In addition, the effects of soil shear strength, elevation amplification factor, seismic coefficient, and ground motion characteristics on the design thrust and pile installation range are further investigated. The limitation that the method applies only to single-row anti-slide pile design is also noted. The research findings provide important reference for seismic design of anti-slip pile structures for slopes.